Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 866
interventional 635
Observational 220
Registry 11

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 295
Drug|placebo 102
Device 60
Other 48
Behavioral 44
Procedure 21
Dietary Supplement 17
Diagnostic Test 12
Behavioral|Other 7
Drug|Other 6
Device|placebo 3
Device|Procedure 3
Drug|Procedure 3
Behavioral|Procedure 2
Biological 2
Radiation 2
Behavioral|Drug 1
Biological|placebo 1
Combination Product 1
Device|Other 1
Dietary Supplement|Drug 1
Dietary Supplement|placebo 1
Genetic 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 200
NA 88
France 45
United Kingdom 19
Japan 15
Belgium 13
Portugal 12
Canada 11
China 11
Germany 11
Korea, Republic of 10
Brazil 8
United States|Canada 8
India 7
Denmark 5
Switzerland 5
Taiwan 5
Netherlands 4
Egypt 3
Iran, Islamic Republic of 3
Mexico 3
Norway 3
South Africa 3
Australia 2
Belgium|Bulgaria|Germany|Hungary|Netherlands|Spain 2
China|Japan 2
Congo, The Democratic Republic of the 2
France|Germany 2
Hong Kong 2
Italy 2
Netherlands|Spain|Sweden 2
Saudi Arabia 2
Spain|United Kingdom 2
United States|Argentina|Brazil|Canada|Mexico 2
United States|Australia|Canada|China|Israel|Poland|Portugal|Spain 2
United States|Austria|Belgium|Brazil|Bulgaria|Canada|Czechia|Estonia|Finland|France|Germany|Hong Kong|Hungary|India|Italy|Japan|Korea, Republic of|Latvia|Lithuania|Mexico|Netherlands|Poland|Puerto Rico|Russian Federation|Spain|Sweden|Taiwan|United Kingdom 2
United States|Belgium|France|Germany|Mexico|Turkey 2
United States|Brazil|Germany|Mexico 2
United States|Bulgaria|Canada|Croatia|Mexico|Poland|Romania|Russian Federation 2
United States|Italy 2
United States|Korea, Republic of|Mexico 2
Australia|Austria|Belgium|Bulgaria|Czech Republic|Denmark|Finland|France|Germany|Greece|Hungary|Ireland|Italy|Netherlands|Norway|Poland|Romania|Russian Federation|Slovakia|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
Australia|Austria|Belgium|Canada|Germany|Netherlands|Poland|Portugal|Spain|United Kingdom| 1
Australia|Austria|Belgium|Finland|France|Germany|Italy|Netherlands|South Africa|Spain|Sweden|Switzerland|United Kingdom 1
Austria|Belgium|Czechia|Germany|Hong Kong|India|Italy|Korea, Republic of|Norway|Russian Federation|Singapore|South Africa|Sweden|Taiwan|Ukraine 1
Austria|Bosnia and Herzegovina|Croatia|Czechia|France|Germany|Hungary|Italy|Malaysia|Moldova, Republic of|Philippines|Poland|Portugal|Romania|Russian Federation|Serbia|Slovakia|Spain|Taiwan|Ukraine|United Kingdom 1
Austria|Bulgaria|Croatia|Czechia|France|Germany|Poland|Portugal|Romania|Spain 1
Austria|Canada|France|Germany|Italy|Lithuania|Spain|United Kingdom| 1
Austria|Czechia|Denmark|Germany|Italy|Portugal|Romania|Spain 1
Austria|Finland 1
Bangladesh|United Kingdom 1
Belgium|Bulgaria|China|Colombia|Czech Republic|Estonia|Finland|France|Germany|Hong Kong|Hungary|India|Ireland|Italy|Korea, Republic of|Latvia|Lithuania|Mexico|Netherlands|Norway|Portugal|Romania|Singapore|Slovakia|Spain|Sweden|Taiwan|Thailand|United Kingdom 1
Belgium|Bulgaria|Denmark|France|Germany|Italy|Netherlands|Poland|Russian Federation|Spain|Thailand|Ukraine 1
Belgium|Bulgaria|Finland|France|Poland|Switzerland 1
Belgium|Bulgaria|France|Germany|Italy|Netherlands|Poland|Russian Federation|Thailand|Ukraine 1
Belgium|Czech Republic|Denmark|France|Germany|Greece|Hungary|Italy|Netherlands|Norway|Portugal|Spain|Sweden|Turkey| 1
Belgium|Czech Republic|Finland|France|Germany|Netherlands|Poland|Spain|United Kingdom 1
Belgium|Estonia|France|Hungary|Italy|Latvia|Poland|Spain|Ukraine 1
Bulgaria|Finland|France|Germany|Japan|Korea, Republic of|Latvia|Mexico|Philippines|Poland|Romania|Russian Federation|Sweden|Switzerland|Ukraine 1
Bulgaria|Netherlands 1
Bulgaria|United States|Australia|Belgium|Canada|Czechia|Finland|France|Germany|Greece|Hungary|Italy|Japan|Korea, Republic of|Latvia|Lithuania|Mexico|Philippines|Poland|Portugal|Romania|Russian Federation|Slovakia|Spain|Sweden|Switzerland|Thailand|Ukraine|United Kingdom 1
Burkina Faso 1
Costa Rica|El Salvador|Guatemala|Peru 1
Croatia|Czechia|United States|Argentina|Australia|Belgium|Brazil|Bulgaria|China|Colombia|Estonia|France|Georgia|Greece|Hungary|Israel|Italy|Korea, Republic of|Latvia|Lithuania|Mexico|Moldova, Republic of|Montenegro|Philippines|Poland|Portugal|Romania|Russian Federation|Serbia|Slovakia|Slovenia|Taiwan|Thailand|Ukraine|United Kingdom 1
Czech Republic|France|United States|Belgium|Brazil|Canada|Germany|Hungary|India|Italy|Mexico|Poland|Romania|Russian Federation|South Africa|United Kingdom 1
Czechia|Bulgaria|Canada|United States|Australia|Belgium|France|Germany|Hungary|Italy|Japan|Lithuania|Mexico|Poland|Portugal|Slovakia|Spain|Turkey|United Kingdom 1
Estonia|France|United States|Australia|Hungary|Italy|Latvia|Lebanon|Lithuania|Netherlands|Portugal|Slovakia|Spain|Turkey 1
Finland|India|Mexico|Russian Federation|South Africa|Ukraine 1
Germany|United States|Austria|Belgium|Canada|Czechia|Finland|France|Hong Kong|Hungary|Israel|Italy|Korea, Republic of|Netherlands|Norway|Poland|Russian Federation|Serbia|Singapore|South Africa|Spain|Sweden|Switzerland|Taiwan|Tunisia|Ukraine 1
Hong Kong|Malaysia|Philippines|Singapore|Taiwan|Thailand 1
India|Australia|Denmark|France|Germany|Greece|Hungary|Italy|Korea, Republic of|Montenegro|Poland|Russian Federation|Serbia|Slovakia|South Africa|Spain|Sweden|Switzerland|Taiwan|United Kingdom 1
India|Belgium|Finland|France|Germany|Hungary|Italy|Netherlands|Poland|Spain|Switzerland|United Kingdom 1
India|United Kingdom 1
Israel 1
Italy|Netherlands|Poland|Russian Federation|Ukraine 1
Italy|United States|Argentina|Australia|Estonia|France|Hungary|Latvia|Lebanon|Lithuania|Netherlands|Portugal|Puerto Rico|Slovakia|Turkey 1
Japan| 1
Japan|China 1
Japan|Korea, Republic of 1
Japan|Malaysia|Philippines|Singapore|Taiwan|Thailand 1
Korea, Republic of|Malaysia|Thailand 1
Malaysia 1
Nigeria 1
Peru 1
Poland|Sweden|Czechia|Hungary 1
Poland|United States|Argentina|Australia|Belgium|Bulgaria|Colombia|Croatia|Czechia|Estonia|Georgia|Hungary|Israel|Italy|Korea, Republic of|Latvia|Lithuania|Mexico|Montenegro|Romania|Russian Federation|Serbia|Slovakia|Slovenia|Taiwan|Thailand|Ukraine|United Kingdom 1
Poland|United States|Argentina|Australia|Belgium|Canada|Chile|Germany|Greece|India|Israel|New Zealand|Russian Federation|South Africa|Spain 1
Romania 1
Romania|Mexico|United States|Austria|Bulgaria|Czechia|Denmark|Finland|France|Greece|Italy|Russian Federation|Spain|Switzerland|Turkey 1
Romania|Slovakia 1
Russian Federation 1
Slovakia|Australia|Denmark|France|Germany|Greece|Hungary|India|Italy|Korea, Republic of|Poland|Russian Federation|Serbia|South Africa|Spain|Sweden|Taiwan|United Kingdom 1
Sweden 1
Turkey 1
United States|Argentina|Australia|Austria|Belgium|Canada|France|Germany|Hungary|Philippines|Poland|Russian Federation|South Africa|Taiwan 1
United States|Argentina|Australia|Belgium|Canada|Chile|Finland|France|Hungary|India|Israel|Korea, Republic of|Mexico|Netherlands|New Zealand|Norway|Poland|Russian Federation|South Africa|Spain|Taiwan|Thailand|Ukraine 1
United States|Argentina|Australia|Belgium|Canada|Chile|Germany|Greece|Hungary|India|Israel|New Zealand|Poland|Russian Federation|South Africa|Spain 1
United States|Argentina|Belgium|Brazil|Canada|Cyprus|France|Germany|Greece|Italy|Poland 1
United States|Argentina|Bosnia and Herzegovina|Bulgaria|Czechia|Germany|Hong Kong|Hungary|India|Malaysia|Mexico|Poland|Puerto Rico|Romania|Russian Federation|Serbia|Singapore|Thailand 1
United States|Argentina|Brazil|Bulgaria|China|Croatia|Czechia|France|Georgia|Greece|Hungary|Israel|Italy|Korea, Republic of|Mexico|Moldova, Republic of|Philippines|Poland|Portugal|Romania|Russian Federation|Serbia|Slovakia|Taiwan|Thailand|Ukraine 1
United States|Argentina|Brazil|Chile|Germany|India|Korea, Republic of|Malaysia|Puerto Rico|Russian Federation|Ukraine 1
United States|Argentina|Brazil|Chile|Germany|India|Korea, Republic of|Puerto Rico|Russian Federation|Ukraine 1
United States|Argentina|Chile|Costa Rica|Korea, Republic of|Puerto Rico|Russian Federation|Ukraine 1
United States|Argentina|Chile|Peru 1
United States|Argentina|Hungary|Netherlands|Poland|Russian Federation|Spain|United Kingdom 1
United States|Australia|Austria|Belgium|Czechia|Germany|Lithuania|Spain 1
United States|Australia|Austria|Canada|Denmark|France|Germany|Ireland|Italy|Poland|Puerto Rico|Spain|United Kingdom 1
United States|Australia|Belarus|India|Lithuania 1
United States|Australia|Belgium|Bosnia and Herzegovina|Bulgaria|Canada|Croatia|Czechia|Denmark|Estonia|Finland|France|Germany|Greece|Hungary|Ireland|Italy|Japan|Lithuania|Mexico|Poland|Romania|Serbia|Slovakia|Spain|Turkey|United Kingdom 1
United States|Australia|Belgium|Brazil|Bulgaria|China|Czechia|France|Germany|Hungary|Israel|Italy|Japan|Korea, Republic of|Mexico|Poland|Portugal|Romania|Russian Federation|Slovakia|Spain|Taiwan 1
United States|Australia|Belgium|Bulgaria|Canada|Czechia|Finland|France|Germany|Greece|Hungary|Italy|Japan|Korea, Republic of|Latvia|Lithuania|Mexico|Philippines|Poland|Portugal|Romania|Russian Federation|Slovakia|Spain|Sweden|Switzerland|Thailand|Ukraine|United Kingdom 1
United States|Australia|Belgium|Canada|Czechia|France|Germany|Hungary|Italy|Spain|Sweden 1
United States|Australia|Belgium|Czechia|Hungary|India|Korea, Republic of|Latvia|Poland|Spain|Thailand 1
United States|Australia|Belgium|France|Germany|Hungary|Israel|Poland|Russian Federation|South Africa|Spain|Ukraine|United Kingdom 1
United States|Australia|Brazil|Bulgaria|China|Czechia|France|Germany|Hungary|Israel|Italy|Japan|Korea, Republic of|Mexico|Poland|Portugal|Romania|Russian Federation|Slovakia|Spain|Taiwan 1
United States|Australia|Brazil|Canada|India|Mexico 1
United States|Australia|Brazil|Canada|Mexico 1
United States|Australia|Bulgaria|Denmark|France|Germany|Romania|Spain|Sweden 1
United States|Australia|Canada|Denmark|Germany|Italy|Poland|Spain|United Kingdom 1
United States|Australia|France|Hungary|Italy|Netherlands|Poland 1
United States|Australia|Jamaica 1
United States|Belarus|Belgium|Bosnia and Herzegovina|Bulgaria|China|Czechia|France|Germany|Greece|Hungary|India|Israel|Italy|Korea, Republic of|Lebanon|Malaysia|Montenegro|Philippines|Poland|Romania|Russian Federation|Serbia|Singapore|Slovakia|Spain|Taiwan|Thailand|Turkey|Ukraine|United Kingdom 1
United States|Belgium 1
United States|Belgium|China|France|Germany|Hungary|Italy|Japan|Mexico|Poland|Ukraine 1
United States|Belgium|Czechia|Denmark|France|Germany|Spain 1
United States|Belgium|Czechia|France|Germany|Hungary|Ireland|Italy|Mexico|Netherlands|Poland|Spain|United Kingdom 1
United States|Belgium|Czechia|Mexico|Poland|Spain 1
United States|Belgium|Mexico 1
United States|Brazil|India|Mexico 1
United States|Bulgaria|Canada|Czechia|Serbia|Ukraine 1
United States|Bulgaria|Czech Republic|Serbia|Ukraine 1
United States|Bulgaria|Czechia|Hungary|India|Korea, Republic of|Mexico|Poland|Thailand 1
United States|Bulgaria|Czechia|Hungary|Poland|Slovakia|Ukraine 1
United States|Canada|South Africa 1
United States|Canada|Spain|United Kingdom 1
United States|Czech Republic|Hong Kong|Ukraine 1
United States|Czechia|Germany|Hungary|Italy|Mexico|Spain 1
United States|Czechia|Germany|Poland 1
United States|Czechia|Latvia 1
United States|Estonia|Hungary|Lithuania|Ukraine 1
United States|Finland 1
United States|France|Germany|Spain 1
United States|France|Germany|Spain|United Kingdom 1
United States|France|Hungary|Mexico|Poland 1
United States|Germany 1
United States|Hungary|Italy|Poland|Ukraine 1
United States|India 1
United States|India|Korea, Republic of|Poland 1

Sites per Study

Site_count Study_Count
1 371
2 38
3 10
4 13
5 12
6 8
7 5
8 7
9 6
10 6
11 5
12 9
13 4
14 5
15 4
16 1
17 2
18 6
19 1
20 2
21 2
22 1
23 4
24 1
25 5
26 1
27 2
28 1
29 2
30 2
31 3
32 3
33 1
34 1
35 2
36 1
37 2
38 1
39 1
40 1
42 2
43 2
44 3
45 1
46 2
47 1
48 1
51 2
53 2
54 2
55 1
56 1
57 1
58 3
60 1
61 1
62 1
63 2
65 1
66 1
67 2
68 1
69 1
70 4
73 1
74 2
76 2
80 2
82 2
84 1
85 1
86 1
87 1
88 1
89 1
91 1
94 1
100 1
102 1
103 2
106 1
108 1
109 1
115 1
118 1
122 1
133 1
140 1
146 1
148 3
150 1
151 1
153 1
155 1
158 1
161 1
162 1
184 2
207 1
231 1

Phase

Phase Study_Count
N/A 195
Phase 3 161
Phase 2 104
Phase 1 80
Phase 4 69
Phase 1/Phase 2 13
Phase 2/Phase 3 11
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 208
2 235
3 60
4 26
5 11
6 5
7 1
8 2
9 1
10 1
NA 85

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 30 2.0000 1.0000 6 5.00000 16.0000 7.0000 2.00
1st Qu. 30 20.0000 16.7500 10 19.25000 40.5000 80.0000 31.50
Median 30 47.5000 24.0000 20 45.50000 90.0000 203.0000 76.00
Mean 30 106.0258 36.6625 27 80.29412 158.4545 271.4534 138.75
3rd Qu. 30 100.0000 40.0000 30 100.00000 99.5000 400.0000 155.50
Max. 30 2000.0000 209.0000 65 600.00000 1000.0000 1701.0000 1541.00

Trial Group Type

group_type Group_Count
Experimental 655
Active Comparator 199
Placebo Comparator 110
NA 85
Other 73
No Intervention 38
Sham Comparator 14

Intervention Model

intervention_model Study_Count
Parallel Assignment 277
Single Group Assignment 268
Crossover Assignment 73
NA 13
Sequential Assignment 4

Primary Purpose

primary_purpose Study_Count
Treatment 461
Diagnostic 37
Basic Science 34
Other 31
Supportive Care 28
NA 21
Prevention 14
Health Services Research 5
Device Feasibility 3
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 92
NA 35
France 18
Egypt 6
United Kingdom 6
China 5
Germany 5
Switzerland 5
Canada 3
Korea, Republic of 3
Norway 3
Spain 3
Belgium 2
Japan 2
Netherlands 2
United States|United Kingdom 2
Austria 1
Austria|Belgium|Canada|Finland|Germany|Hungary|Italy|Netherlands|Poland|Portugal|Russian Federation|Saudi Arabia|Sweden|United Kingdom 1
Austria|Belgium|Czechia|Israel|Sweden|United Kingdom 1
Belgium|Canada|France|Germany|Italy|Netherlands|United Kingdom 1
France|Germany|Greece|Italy|Poland|Spain|United Kingdom 1
France|Germany|Netherlands|Spain|United Kingdom 1
Germany|Austria 1
Germany|Austria|Czech Republic|Italy|Poland|Romania|Spain 1
Germany|Netherlands|United Kingdom 1
Greece 1
India 1
Israel 1
Italy 1
Netherlands|France|Germany|Italy|Spain|United Kingdom 1
Portugal 1
Slovakia 1
Taiwan 1
Tanzania 1
Thailand 1
Turkey 1
Ukraine 1
United Kingdom|Denmark|Germany|Hungary|Ireland|Italy|Netherlands|Norway|Spain 1
United States|Argentina|Australia 1
United States|Argentina|Canada|Greece|Italy|Spain|United Kingdom 1
United States|Belgium|Germany|Israel|United Kingdom 1
United States|Canada 1
United States|Canada|Czechia|Denmark|Estonia|France|Italy|Norway|United Kingdom 1
United States|Canada|Israel|Singapore|United Kingdom 1

Sites per Study

Site_count Study_Count
1 169
2 13
3 4
4 1
5 2
6 1
7 2
8 1
9 1
10 2
11 2
12 1
13 1
15 1
18 1
20 2
21 1
24 1
25 1
27 1
28 1
33 1
42 2
43 1
44 1
52 1
54 2
61 1
62 1
113 1

Enrollment Metrics

Measure Observational
Min 1.000
1st Qu 50.000
Median 100.000
Mean 581.895
3rd Qu 323.000
Max 20000.000

Observation Model

observational_model Study_Count
Cohort 96
NA 44
Case-Only 30
Case-Control 21
Case Control 12
Other 7
Family-Based 4
Defined Population 2
Ecologic or Community 2
Case-Crossover 1
Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 138
Retrospective 30
Cross-Sectional 22
NA 22
Other 5
Cross-Sectional, Retrospective 1
Longitudinal, Prospective 1
Longitudinal, Retrospective/Prospective 1

Registries

Studies by Country

Country Study_Count
Belgium 1
Denmark 1
Finland 1
France 1
Iran, Islamic Republic of 1
Netherlands 1
Turkey 1
United States|Australia 1
United States|Australia|Austria|Belgium|Canada|China|India|Israel|Italy|Japan|Netherlands|Poland|Portugal|Spain|United Kingdom 1
United States|Australia|Canada 1
United States|Finland 1

Sites per Study

Site_count Study_Count
1 6
2 2
9 1
30 1
57 1

Enrollment Metrics

Measure Registries
Min 23.000
1st Qu 40.500
Median 205.000
Mean 2199.818
3rd Qu 786.000
Max 20000.000

Registry Model

observational_model Study_Count
Cohort 6
Case-Control 2
Case-Only 1
Case Control 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 9
Cross-Sectional 2

Follow-up

target_duration Study_Count
1 Week 2
2 Years 2
3 Years 2
10 Years 1
100 Years 1
4 Weeks 1
5 Years 1
7 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03346382 Emergency Medical Services and Epilepsy in Switzerland https://ClinicalTrials.gov/show/NCT03346382 Completed Balgrist University Hospital 2015-12-31
NCT03400371 Biology of Juvenile Myoclonic Epilepsy https://ClinicalTrials.gov/show/NCT03400371 Recruiting King’s College London 2020-01-31
NCT03376087 Cardiac Rhythm Disturbances in Hard-to-treat Epilepsy Patients Using Loop ECG Recorders https://ClinicalTrials.gov/show/NCT03376087 Completed National Research Center for Preventive Medicine 2019-12-15
NCT03369522 Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram https://ClinicalTrials.gov/show/NCT03369522 Recruiting University Hospital, Lille 2020-01-31
NCT03822741 Etiology and Treatment of Neonatal Seizure https://ClinicalTrials.gov/show/NCT03822741 Recruiting Children’s Hospital of Fudan University 2021-12-30
NCT03321240 Study of Predictive Biomarkers for Rational Management of Drug-resistant Epilepsy Associated With Focal Cortical Dysplasia https://ClinicalTrials.gov/show/NCT03321240 Recruiting University Hospital, Strasbourg, France 2022-12-15
NCT03278210 National Study on the Interest of EEG-fMRI in the Presurgical Evaluation of Partial Epilepsies Drug https://ClinicalTrials.gov/show/NCT03278210 Recruiting University Hospital, Lille 2020-04-30
NCT03265925 Brain Network Activation Analysis in Epilepsy https://ClinicalTrials.gov/show/NCT03265925 Completed ElMindA Ltd 2018-05-08
NCT03208660 Study to Investigate Dosage, Efficacy, and Safety of Fycompa in Routine Clinical Care of Patients With Epilepsy https://ClinicalTrials.gov/show/NCT03208660 Completed Eisai Inc. 2019-03-15
NCT03196466 Population Pharmacokinetics of Antiepileptic in Pediatrics https://ClinicalTrials.gov/show/NCT03196466 Recruiting Assistance Publique - Hôpitaux de Paris 2022-06-19
NCT03123302 Our Anesthesia Experience During MRI Scan https://ClinicalTrials.gov/show/NCT03123302 Completed Akdeniz University 2018-02-01
NCT03103841 Investigation of Sleep Quality and Prevalence of Sleep-disordered Breathing in Children and Young People With Epilepsy https://ClinicalTrials.gov/show/NCT03103841 Recruiting NHS Lothian 2020-04-28
NCT03097809 SEEG Investigation of Mood Dysregulation in Epilepsy https://ClinicalTrials.gov/show/NCT03097809 Enrolling by invitation The Cleveland Clinic 2020-12-31
NCT03082222 ZEDEBAC: Zebinix Effects in Dependency of Baseline Conditions https://ClinicalTrials.gov/show/NCT03082222 Completed Eisai Inc. 2018-10-29
NCT03059381 Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adolescence Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures https://ClinicalTrials.gov/show/NCT03059381 Active, not recruiting Eisai Inc. 2022-02-28
NCT03059329 Investigation of the Clinical Safety and Efficacy of Long-term Treatment With Fycompa Tablets in Adult Epilepsy Patients With Partial-onset Seizures (With or Without Secondary Generalized Seizures) or Primary Generalized Tonic-clonic Seizures https://ClinicalTrials.gov/show/NCT03059329 Completed Eisai Inc. 2019-09-13
NCT02993861 Pharmacokinetics of Anti-epileptic Drugs in Obese Children https://ClinicalTrials.gov/show/NCT02993861 Completed Duke University 2019-10-10
NCT02926703 Lactate Compared to Creatine Kinase as Diagnostic Marker in Generalized Epileptic Seizure https://ClinicalTrials.gov/show/NCT02926703 Completed RWTH Aachen University 2016-08-31
NCT02911025 Effects of Clobazam on Sleep and Daytime Function in Patients With Epilepsy https://ClinicalTrials.gov/show/NCT02911025 Completed Brigham and Women’s Hospital 2017-12-31
NCT02899832 A Study of Hemodynamic Changes Using Near Infra-red Spectrometry (NIRS) in Infantile Epilepsy Spasms https://ClinicalTrials.gov/show/NCT02899832 Recruiting Centre Hospitalier Universitaire, Amiens 2020-02-29
NCT02898935 Improvement of the Accuracy of Spatial Representation of Invasive Exploratory Electrodes in Focal Epilepsy https://ClinicalTrials.gov/show/NCT02898935 Completed Fondation Ophtalmologique Adolphe de Rothschild 2018-05-31
NCT02890641 Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies https://ClinicalTrials.gov/show/NCT02890641 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2030-12-31
NCT02883712 Study of Predictors of Response to Anti Epilepsy in Epilepsy https://ClinicalTrials.gov/show/NCT02883712 Recruiting University Hospital, Lille 2021-12-31
NCT02854384 Mobile Phone Radiation and Brain Rhythm in Epileptic Patients https://ClinicalTrials.gov/show/NCT02854384 Completed Kasr El Aini Hospital 2015-08-31
NCT02826915 Electro- Hemodynamic Activity in Children: Combined Analysis by Video -EEG Spectroscopy and Near-infrared (NIRS ) https://ClinicalTrials.gov/show/NCT02826915 Recruiting Centre Hospitalier Universitaire, Amiens 2018-11-30
NCT02814331 Electrohaemodynamic Activity in Epileptic Children : Combined Video-EEG and Near-infrared Spectroscopy (NIRS) Analysis https://ClinicalTrials.gov/show/NCT02814331 Completed Centre Hospitalier Universitaire, Amiens 2015-04-24
NCT02802475 Antibodies Causing Epilepsy Syndromes: The ACES Study. https://ClinicalTrials.gov/show/NCT02802475 Recruiting Erasmus Medical Center 2019-01-31
NCT02736162 Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy https://ClinicalTrials.gov/show/NCT02736162 Completed Eisai Inc. 2016-06-30
NCT02722590 Post-Marketing Surveillance Study of Fycompa Film-coated Tablets in Korean Patients https://ClinicalTrials.gov/show/NCT02722590 Recruiting Eisai Inc. 2021-06-30
NCT02694094 Impact of Ketogenic Diets on Cardiovascular Health in Adults With Epilepsy https://ClinicalTrials.gov/show/NCT02694094 Enrolling by invitation Johns Hopkins University 2022-12-31
NCT02687711 Study to Look at How Effective Briviact is as add-on Treatment for Patients With Epilepsy With Partial Onset Seizures https://ClinicalTrials.gov/show/NCT02687711 Active, not recruiting UCB Pharma 2020-07-31
NCT02639325 Tumor Related Epilepsy https://ClinicalTrials.gov/show/NCT02639325 Recruiting National Institutes of Health Clinical Center (CC) 2025-12-31
NCT02824822 Genetic Markers of Cardiovascular Disease in Epilepsy https://ClinicalTrials.gov/show/NCT02824822 Recruiting Mayo Clinic 2022-12-31
NCT02813980 Neural Circulatory Control and SUDEP Risk. https://ClinicalTrials.gov/show/NCT02813980 Recruiting Mayo Clinic 2022-05-31
NCT03404128 Long Term Follow-up of Hippocampal DBS for Refractory Epilepsy https://ClinicalTrials.gov/show/NCT03404128 Active, not recruiting University Hospital, Ghent 2020-10-31
NCT01858285 Genetics of Severe Early Onset Epilepsies https://ClinicalTrials.gov/show/NCT01858285 Recruiting Boston Children’s Hospital 2030-12-31
NCT01273129 Surgery as a Treatment for Medically Intractable Epilepsy https://ClinicalTrials.gov/show/NCT01273129 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT02555410 Seizure Detection and Warning System in Epilepsy Patients https://ClinicalTrials.gov/show/NCT02555410 Completed Brain Sentinel 2017-07-07
NCT02523183 The Use of Medicinal Cannabinoids as Adjunctive Treatment for Medically Refractory Epilepsy https://ClinicalTrials.gov/show/NCT02523183 Active, not recruiting University of Colorado, Denver 2020-10-31
NCT02491073 Study to Evaluate Serum Free Thyroxine (FT4) and Free Triiodothyronine (FT3) Measurements for Subjects Treated With Eslicarbazeine Acetate (ESL) https://ClinicalTrials.gov/show/NCT02491073 Completed Sunovion 2016-03-31
NCT02453763 In Vivo Imaging of Therapeutic Electric Current Flow https://ClinicalTrials.gov/show/NCT02453763 Completed University of Florida 2017-07-06
NCT02447198 Cannabidiol (CBD) and Pediatric Epilepsy https://ClinicalTrials.gov/show/NCT02447198 Completed University of Colorado, Denver 2018-09-11
NCT02415686 Cardiac Arrhythmias in Dravet Syndrome https://ClinicalTrials.gov/show/NCT02415686 Completed Stichting Epilepsie Instellingen Nederland 2018-08-29
NCT02410889 EEG-fMRI: Towards a Useful Clinical Tool in Epilepsy https://ClinicalTrials.gov/show/NCT02410889 Completed University of Birmingham 2016-01-31
NCT04259125 Evaluating the Role of Inflammation in Neonatal Epileptogenesis https://ClinicalTrials.gov/show/NCT04259125 Recruiting University of California, San Francisco 2023-05-31
NCT02403843 RNS® System Epilepsy PAS https://ClinicalTrials.gov/show/NCT02403843 Enrolling by invitation NeuroPace 2023-05-31
NCT02371200 Detecting Generalized Tonic-Clonic Seizures With a Seizure Detection and Warning System in Epilepsy Patients https://ClinicalTrials.gov/show/NCT02371200 Completed Brain Sentinel 2017-12-31
NCT02356731 LevetIracetam in Patients Being Treated for Epilepsy https://ClinicalTrials.gov/show/NCT02356731 Completed Elpen Pharmaceutical Co. Inc. 2016-12-31
NCT02320136 Recording High Frequency Oscillations in Patients With Tumors and Epilepsy https://ClinicalTrials.gov/show/NCT02320136 Enrolling by invitation University of Zurich 2024-12-31
NCT02276053 Study of Lacosamide as an Adjunctive Drug Treatment for Epilepsy in Patients With Brain Tumors https://ClinicalTrials.gov/show/NCT02276053 Completed UCB Pharma 2017-12-04
NCT02269397 Proof of Principle for a Diagnostic Blood Test of Recurrent Seizures https://ClinicalTrials.gov/show/NCT02269397 Completed Cognizance Biomarkers, LLC 2015-07-14
NCT02132507 Multimodal Functional Neuroimaging in Epilepsy Patients https://ClinicalTrials.gov/show/NCT02132507 Completed University of Minnesota 2015-06-30
NCT02100501 Prospective Study of Comparison Between the Modified Atkins Diet and Classic Ketogenic Diet for Intractable Childhood Epilepsy https://ClinicalTrials.gov/show/NCT02100501 Completed Yonsei University 2013-03-31
NCT01296880 Effects of Adjunctive Lacosamide on Mood States and Quality of Life (QOL) in Patients With Epilepsy https://ClinicalTrials.gov/show/NCT01296880 Completed State University of New York - Downstate Medical Center 2014-07-31
NCT01281293 Vagus Nerve Stimulation Clinical Outcomes Measured Prospectively in Patients Stimulated https://ClinicalTrials.gov/show/NCT01281293 Completed LivaNova 2018-08-16
NCT01281280 PuLsE 2-Observational Long-Term Effectiveness Follow-Up Study of PuLsE 1 https://ClinicalTrials.gov/show/NCT01281280 Completed Cyberonics, Inc. 2013-10-31
NCT02033902 A Global, Postmarketing Observational Safety Study to Evaluate the Safety and Tolerability of Fycompa (Perampanel) as Add-on Therapy in Epilepsy Patients Aged Greater Than or Equal to 12 Years https://ClinicalTrials.gov/show/NCT02033902 Completed Eisai Inc. 2018-01-31
NCT01938560 REMS Retigabine Study https://ClinicalTrials.gov/show/NCT01938560 Completed GlaxoSmithKline 2013-05-31
NCT01931644 At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions https://ClinicalTrials.gov/show/NCT01931644 Recruiting Sanguine Biosciences 2025-08-31
NCT01884766 Copeptin in Childhood Epilepsy https://ClinicalTrials.gov/show/NCT01884766 Completed University Hospital, Basel, Switzerland 2015-12-31
NCT01874600 Seizure Detection and Warning System for Epilepsy Patients https://ClinicalTrials.gov/show/NCT01874600 Active, not recruiting Brain Sentinel 2019-12-31
NCT01863602 Special Drug Use Investigation for LAMICTAL® (Long Term) https://ClinicalTrials.gov/show/NCT01863602 Completed GlaxoSmithKline 2016-07-31
NCT01858870 Observational Retrospective Study of Effectivity and Tolerability in Patients With Lacosamide Medication https://ClinicalTrials.gov/show/NCT01858870 Completed Instituto de Investigacion Sanitaria La Fe 2012-12-31
NCT01855178 Pediatric Seizure Movement Bed Alarm https://ClinicalTrials.gov/show/NCT01855178 Completed Le Bonheur Children’s Hospital 2015-06-30
NCT01850498 Epilepsy Motion Sensing https://ClinicalTrials.gov/show/NCT01850498 Completed MedtronicNeuro 2013-04-30
NCT01833247 Lactic Acidosis During and After Seizures https://ClinicalTrials.gov/show/NCT01833247 Completed Stanford University 2014-12-31
NCT01833234 Epilepsy Impact Scale https://ClinicalTrials.gov/show/NCT01833234 Completed Stanford University 2014-09-30
NCT01793532 Study of [11C]DPA-713 for Temporal Lobe Epilepsy https://ClinicalTrials.gov/show/NCT01793532 Completed National Institutes of Health Clinical Center (CC) 2016-06-08
NCT01767779 Potential EEG Biomarkers and Antiepileptogenic Strategies for Epilepsy in TSC https://ClinicalTrials.gov/show/NCT01767779 Completed University of Alabama at Birmingham 2016-12-31
NCT01730170 Maternal and Neurodevelopmental Outcomes of in Utero Antiepileptic Drug (AED) Exposure https://ClinicalTrials.gov/show/NCT01730170 Active, not recruiting Stanford University 2022-08-30
NCT01721213 Trobaltâ„¢ Products Risk Survey https://ClinicalTrials.gov/show/NCT01721213 Completed GlaxoSmithKline 2013-12-31
NCT01682681 An Observational Study to Evaluate Long-term Retention Rate of Topiramate in Participants With Epilepsy https://ClinicalTrials.gov/show/NCT01682681 Completed Janssen Korea, Ltd., Korea 2009-05-31
NCT01673282 Study Evaluating Changes in Total Drug Load and Seizure Frequency Using Vimpat® (Lacosamide) in Combination Therapy https://ClinicalTrials.gov/show/NCT01673282 Completed UCB Pharma 2015-07-31
NCT01663545 Brain P-gp and Inflammation in People With Epilepsy https://ClinicalTrials.gov/show/NCT01663545 Completed National Institutes of Health Clinical Center (CC) NA
NCT01662453 Risk Factors for Sudden Unexplained Death in Epilepsy https://ClinicalTrials.gov/show/NCT01662453 Recruiting NYU Langone Health 2022-09-30
NCT01630785 Neurophysiological Intraoperative or Epilepsy Monitoring https://ClinicalTrials.gov/show/NCT01630785 Enrolling by invitation University of Zurich 2025-12-31
NCT01613911 Study of Human Sensory Perception https://ClinicalTrials.gov/show/NCT01613911 Completed Swedish Medical Center 2014-11-30
NCT01607333 WEUKBRE5557: IMI PROTECT(Work Package 2): Antiepileptics & Suicide https://ClinicalTrials.gov/show/NCT01607333 Completed GlaxoSmithKline 2014-07-31
NCT01587339 Systematic Review: Retigabine for Adjunctive Therapy in Partial Epilepsy https://ClinicalTrials.gov/show/NCT01587339 Completed GlaxoSmithKline 2011-03-31
NCT01566500 Medication Adherence in Individuals With Epilepsy https://ClinicalTrials.gov/show/NCT01566500 Completed Columbia University 2012-03-31
NCT01532726 Eslicarbazepine Acetate as Add-On Treatment to One Baseline Antiepileptic Drug (ESLADOBA) https://ClinicalTrials.gov/show/NCT01532726 Completed Bial - Portela C S.A. 2014-09-30
NCT01521754 Product Surveillance Registry- Deep Brain Stimulation for Epilepsy https://ClinicalTrials.gov/show/NCT01521754 Completed MedtronicNeuro 2019-06-19
NCT03268824 Impact of Epileptic Discharge on the Structural Connectivity of the Developing Brain https://ClinicalTrials.gov/show/NCT03268824 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2021-06-30
NCT01486056 ECG Vector Determination https://ClinicalTrials.gov/show/NCT01486056 Completed Cyberonics, Inc. 2012-01-31
NCT01485016 Physiological and Biomechanical Data Collection Study in Epilepsy Subjects https://ClinicalTrials.gov/show/NCT01485016 Completed Cyberonics, Inc. 2012-05-31
NCT01457989 Meta-Analysis Plan for Pooled Data for Studies VRX-RET-E22-303 and VRX-RET-E22-304 https://ClinicalTrials.gov/show/NCT01457989 Completed GlaxoSmithKline 2011-08-31
NCT01431326 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care https://ClinicalTrials.gov/show/NCT01431326 Completed Duke University 2019-11-30
NCT01390909 Clinical and Economic Burden of Uncontrolled Epilepsy: Analyses From a Medicaid Database and a Private Health Plan Database https://ClinicalTrials.gov/show/NCT01390909 Completed GlaxoSmithKline 2011-01-31
NCT01376180 Drug Use Investigation for LAMICTAL https://ClinicalTrials.gov/show/NCT01376180 Completed GlaxoSmithKline 2016-08-31
NCT01374204 Epilepsy-Associated Stigma https://ClinicalTrials.gov/show/NCT01374204 Completed University Hospital, Limoges 2018-12-31
NCT01373190 Thermographic Examination of Skin Temperatures in Individuals With Focal Onset Epilepsy https://ClinicalTrials.gov/show/NCT01373190 Completed Atlantic University 2012-04-30
NCT01357707 Clinical-genetic Investigations in Children With Early Infantile Epilepsies https://ClinicalTrials.gov/show/NCT01357707 Completed Charite University, Berlin, Germany 2017-12-31
NCT01355211 Putting Electroencephalography (EEG) in the Emergency Department https://ClinicalTrials.gov/show/NCT01355211 Completed Bio-Signal Group Corp. 2012-02-29
NCT01335425 The Rolandic Epilepsy/ESES/Landau-Kleffner Syndrome and Correlation With Language Impairment Study https://ClinicalTrials.gov/show/NCT01335425 Completed Maastricht University Medical Center 2013-12-31
NCT01332539 An Observational Study to Assess the Burden of Drug-resistant Partial Epilepsy in Italy https://ClinicalTrials.gov/show/NCT01332539 Completed GlaxoSmithKline 2012-11-30
NCT04398667 European Non-interventional Study on Refractory Epilepsy With Developmental Delay. https://ClinicalTrials.gov/show/NCT04398667 Recruiting Zogenix, Inc. 2020-06-30
NCT04376671 Quantitative EEG Markers in Mild Cognitive Impairment in Epilepsy https://ClinicalTrials.gov/show/NCT04376671 Completed Mansoura University Hospital 2020-02-01
NCT04357236 18F-FDG PET Imaging Analysis of Antiepileptic Drug Response in BECTS https://ClinicalTrials.gov/show/NCT04357236 Completed Second Affiliated Hospital, School of Medicine, Zhejiang University 2020-03-30
NCT04264780 Epilepsy Surgery and Cognitive Outcome https://ClinicalTrials.gov/show/NCT04264780 Enrolling by invitation Oslo University Hospital 2022-06-30
NCT04230044 A Study to Evaluate the Safety and Efficacy of Fycompa® (Perampanel) as Add-on Therapy in Participants With Epilepsy https://ClinicalTrials.gov/show/NCT04230044 Completed Eisai Inc. 2017-07-03
NCT04221282 ZEBinix® Retention Rate in Epilepsy in Elderly Patients https://ClinicalTrials.gov/show/NCT04221282 Recruiting Centre Hospitalier Saint Joseph Saint Luc de Lyon 2020-09-30
NCT04204863 Status Epilepticus Unicenter Population (STEP UP) Study https://ClinicalTrials.gov/show/NCT04204863 Recruiting University Hospital, Basel, Switzerland 2021-12-31
NCT04191863 Sleep Architecture in Valproate-induced Nocturnal Enuresis in Primary School and Preschool Children. https://ClinicalTrials.gov/show/NCT04191863 Completed Mansoura University Hospital 2019-06-01
NCT04169581 A Deep Learning Framework for Pediatric TLE Detection Using 18F-FDG-PET Imaging https://ClinicalTrials.gov/show/NCT04169581 Completed Second Affiliated Hospital, School of Medicine, Zhejiang University 2019-02-28
NCT04132063 Generic Substitution of Original Levetiracetam in Thai Epilepsy Patients https://ClinicalTrials.gov/show/NCT04132063 Completed Mahidol University 2019-05-30
NCT04095247 Does Pulse-triggered VNS Autostimulation Increase VNS Efficacy https://ClinicalTrials.gov/show/NCT04095247 Enrolling by invitation Oslo University Hospital 2025-12-31
NCT04061707 Subcutaneous EEG: Forecasting of Epileptic Seizures https://ClinicalTrials.gov/show/NCT04061707 Recruiting King’s College London 2021-05-15
NCT03953781 Effect of Valproate Versus Levetiracetam Monotherapy on Reproductive Functions in Epileptic Males https://ClinicalTrials.gov/show/NCT03953781 Completed Zagazig University 2017-03-31
NCT03934268 A Cohort Study on the Prognosis of Neonatal KCNQ2 Gene-associated Epileptic Encephalopathy https://ClinicalTrials.gov/show/NCT03934268 Recruiting Children’s Hospital of Fudan University 2022-12-31
NCT03926273 Serum and Urine Ghrelin in Adult Epileptic Patients https://ClinicalTrials.gov/show/NCT03926273 Completed Zagazig University 2019-01-30
NCT03876093 Epilepsy-related Brain Tumors Register https://ClinicalTrials.gov/show/NCT03876093 Recruiting Groupe Hospitalier Paris Saint Joseph 2023-12-31
NCT03857451 Treatment of Gait Disorders in Children With Dravet Syndrome https://ClinicalTrials.gov/show/NCT03857451 Active, not recruiting Universiteit Antwerpen 2019-12-31
NCT03848273 Post Stroke Epileptic Seizures Risk Forecast https://ClinicalTrials.gov/show/NCT03848273 Recruiting Lviv National Medical University 2020-12-31
NCT03836924 A Study to Assess Safety and Efficacy of Perampanel in Indian Participants as an Adjunctive Treatment in Partial Onset Seizures With or Without Secondary Generalized Seizures in Participants With Epilepsy Aged 12 Years or Older https://ClinicalTrials.gov/show/NCT03836924 Active, not recruiting Eisai Inc. 2020-02-08
NCT03806946 Impact of Relationship of Epilepsy and Attention Deficit Hyperactive Disorder https://ClinicalTrials.gov/show/NCT03806946 Completed Assiut University 2019-12-30
NCT03800992 Bad News- Diagnosis: Epilepsy in Childhood https://ClinicalTrials.gov/show/NCT03800992 Recruiting University Hospital, Basel, Switzerland 2021-02-28
NCT03775694 Diffusion MRI-1 Imaging Database https://ClinicalTrials.gov/show/NCT03775694 Recruiting Medtronic Surgical Technologies 2021-01-31
NCT03753035 Observance of Anticonvulsant Treatments and Quality of Life of Epileptic Children https://ClinicalTrials.gov/show/NCT03753035 Recruiting Central Hospital, Nancy, France 2019-04-30
NCT01218321 The Effect of Anti-epileptic Drugs on Mitochondrial Activity https://ClinicalTrials.gov/show/NCT01218321 Completed Hadassah Medical Organization 2011-12-31
NCT03653975 Clinical Features and Potential Etiology of Epilepsy and Nodding Syndrome in the Mahenge Area, Ulanga District https://ClinicalTrials.gov/show/NCT03653975 Recruiting Heidelberg University 2019-05-31
NCT03644732 Atlas of Human Cognition by SEEG (MAPCOG-SEEG) https://ClinicalTrials.gov/show/NCT03644732 Recruiting University Hospital, Grenoble 2028-03-31
NCT03643471 Advanced Magnetic Resonance Imaging in Temporal Lobe Epilepsy https://ClinicalTrials.gov/show/NCT03643471 Recruiting Assiut University 2019-09-01
NCT02821260 Clinical Evaluation of the Efficacity of Epilepsy Surgery in Infants and Children https://ClinicalTrials.gov/show/NCT02821260 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2020-12-31
NCT03587506 Periodic Limb Movement and Genetic Generalized Epilepsy https://ClinicalTrials.gov/show/NCT03587506 Completed University of Alexandria 2016-09-30
NCT03583957 A Wireless EEG Patch for Continuous Electrographic Monitoring https://ClinicalTrials.gov/show/NCT03583957 Enrolling by invitation Epitel, Inc. 2020-07-31
NCT03547050 Rolandic Epilepsy Genomewide Association International Study https://ClinicalTrials.gov/show/NCT03547050 Recruiting King’s College London 2020-12-31
NCT03533374 Validation of Criteria for Identification of Epileptiform Discharges in EEG Recordings of Patients With Epilepsy https://ClinicalTrials.gov/show/NCT03533374 Completed Aarhus University Hospital 2018-01-01
NCT03489187 Visualase Visualization Database (VIVID-1) https://ClinicalTrials.gov/show/NCT03489187 Recruiting Medtronic Surgical Technologies 2020-07-31
NCT03478852 Investigating Epilepsy: Screening, Evaluation and Treatment https://ClinicalTrials.gov/show/NCT03478852 Recruiting National Institutes of Health Clinical Center (CC) 2027-07-30
NCT03465566 Emotion Recognition in Benign Epilepsy of Childhood With Centro-Temporal Spikes (BECTS) https://ClinicalTrials.gov/show/NCT03465566 Recruiting Neuromed IRCCS 2020-03-01
NCT01261416 Pharmacokinetics of Levetiracetam (Keppra) in Neonates https://ClinicalTrials.gov/show/NCT01261416 Completed Children’s Hospital Medical Center, Cincinnati 2010-07-31
NCT01259310 Women With Epilepsy: Pregnancy Outcomes and Deliveries https://ClinicalTrials.gov/show/NCT01259310 Completed NYU Langone Health 2015-03-31
NCT01231646 Does Valproate Increase Levels of Folate Receptor Autoantibodies in Women? https://ClinicalTrials.gov/show/NCT01231646 Completed Northwell Health 2013-04-30
NCT01220180 Lyrica (Pregabalin) Korean Post Marketing Surveillance Study https://ClinicalTrials.gov/show/NCT01220180 Completed Pfizer 2011-04-30
NCT01214707 Heart Rate Changes During Normal Activity, Exercise, and Seizures in Subjects With Epilepsy https://ClinicalTrials.gov/show/NCT01214707 Completed Cyberonics, Inc. 2011-10-31
NCT01210690 Observational Study in Infants Who Are Prescribed Treatment With Keppra® (Levetiracetam) Oral Solution https://ClinicalTrials.gov/show/NCT01210690 Completed UCB Pharma 2013-11-30
NCT01202682 Heart Rate Changes During Normal Activity, Exercise, and Sleep in Normal Healthy Subjects With and Without Epilepsy https://ClinicalTrials.gov/show/NCT01202682 Completed Cyberonics, Inc. 2010-10-31
NCT01202669 Heart Rate Changes in Subjects With Epilepsy https://ClinicalTrials.gov/show/NCT01202669 Completed Cyberonics, Inc. 2012-10-31
NCT01198964 Optimization of Human Cortical Stimulation https://ClinicalTrials.gov/show/NCT01198964 Recruiting University of Washington 2020-08-31
NCT01098162 Vimpat® Added as Adjunctive Therapy to One Baseline Antiepileptic Drug https://ClinicalTrials.gov/show/NCT01098162 Completed UCB Pharma 2013-07-31
NCT01086501 ESOXC-ER Efficacy and Safety of an Extended Release (ER) Formulation of Oxcarbazepine (Apydan Extent) in Epileptic Patients https://ClinicalTrials.gov/show/NCT01086501 Completed Desitin Arzneimittel GmbH 2011-07-31
NCT01085461 Assessment of Suicidality in Epilepsy - Rating Tools https://ClinicalTrials.gov/show/NCT01085461 Completed The Epilepsy Study Consortium NA
NCT01030094 A Cross-sectional Study to Investigate the Effect of Topiramate on Bone and Mineral Metabolism in Female Participants With Epilepsy https://ClinicalTrials.gov/show/NCT01030094 Completed Janssen Korea, Ltd., Korea 2009-04-30
NCT00931619 GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression https://ClinicalTrials.gov/show/NCT00931619 Completed National Institutes of Health Clinical Center (CC) NA
NCT00922987 Clinical Study With Lyrica In Patients Suffering From Epilepsy https://ClinicalTrials.gov/show/NCT00922987 Completed Pfizer 2010-06-30
NCT00894478 Improving Lesion Detection in Children With Magnetic Resonance Imaging (MRI)-Negative Partial Epilepsy Using Diffusion Tensor Imaging https://ClinicalTrials.gov/show/NCT00894478 Completed The Hospital for Sick Children 2012-05-31
NCT00870688 Valproate Sustained Release Minitablets (Orfiril(R) Long) Once Daily in the Evening https://ClinicalTrials.gov/show/NCT00870688 Completed Desitin Arzneimittel GmbH 2006-04-30
NCT00859794 An Examination of Cognitive and Sensorimotor Processes in Patients With Epilepsy https://ClinicalTrials.gov/show/NCT00859794 Enrolling by invitation Northwell Health 2019-12-31
NCT04043572 The Biomarkers of Neurological Disease in Utero Study https://ClinicalTrials.gov/show/NCT04043572 Recruiting Nottingham University Hospitals NHS Trust 2025-09-30
NCT01441401 Safety and Efficacy of Gabapen for Pediatric (Regulatory Post Marketing Commitment Plan) https://ClinicalTrials.gov/show/NCT01441401 Completed Pfizer 2014-08-31
NCT02731443 The Impact of Epilepsy Surgery on Dream Content https://ClinicalTrials.gov/show/NCT02731443 Completed London Health Sciences Centre 2018-06-30
NCT02286271 Preliminary Testing of a Novel Device to Detect Epileptic Seizures https://ClinicalTrials.gov/show/NCT02286271 Completed University of Edinburgh 2016-12-31
NCT01657864 WEUSKOP6166: Lamotrigine and Aseptic Meningitis https://ClinicalTrials.gov/show/NCT01657864 Completed GlaxoSmithKline 2012-07-31
NCT04282681 XLTCS - Accelerometer Data Collection in an Epilepsy Monitoring Unit (EMU) https://ClinicalTrials.gov/show/NCT04282681 Recruiting LivaNova 2021-08-28
NCT04076449 Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy https://ClinicalTrials.gov/show/NCT04076449 Recruiting Beijing Tiantan Hospital 2026-12-31
NCT03169751 An Exploratory Trial Using sEMG to Differentiate PNES From Epileptic Seizures https://ClinicalTrials.gov/show/NCT03169751 Active, not recruiting Brain Sentinel 2020-02-01
NCT04095026 Study of Direct Brain Recording and Stimulation for Memory Enhancement https://ClinicalTrials.gov/show/NCT04095026 Enrolling by invitation National Institutes of Health Clinical Center (CC) 2023-12-01
NCT01351727 Epidemiologic Follow Up Study of Newly Diagnosed Epilepsy Among Seniors https://ClinicalTrials.gov/show/NCT01351727 Completed University of Arizona 2014-09-30
NCT04166305 Drug Resistant Epilepsy: Clinical and Genetic Study https://ClinicalTrials.gov/show/NCT04166305 Recruiting Mansoura University Hospital 2020-10-01
NCT04023851 Mobile Application of Seizure Diary (Brain4U) in Epilepsy Care https://ClinicalTrials.gov/show/NCT04023851 Recruiting Seoul National University Hospital 2019-12-31
NCT03860467 Epileptic Seizures in Intensive Care Units https://ClinicalTrials.gov/show/NCT03860467 Recruiting University Hospital, Basel, Switzerland 2020-10-31
NCT00772421 Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy - Recruitment Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy - Recruitment Rhythm https://ClinicalTrials.gov/show/NCT00772421 Completed MedtronicNeuro 2010-05-31
NCT00736424 Brain Stimulation for Epilepsy Long Term Follow-up https://ClinicalTrials.gov/show/NCT00736424 Completed MedtronicNeuro 2010-11-30
NCT00706160 Language Mapping in Patients With Epilepsy https://ClinicalTrials.gov/show/NCT00706160 Completed National Institutes of Health Clinical Center (CC) NA
NCT00687024 Determining the Extent of Diffusion Tensor Abnormalities in Focal Cortical Dysplasia https://ClinicalTrials.gov/show/NCT00687024 Completed The Hospital for Sick Children 2013-06-30
NCT00684424 Non-Interventional Study With LYRICA (Pregabalin) In Patients With Epilepsy As Adjunctive Therapy Of Partial Seizures To Reduce Seizure Frequency https://ClinicalTrials.gov/show/NCT00684424 Completed Pfizer 2009-03-31
NCT00642564 Study on Migraine and Headache in Epileptic Patients https://ClinicalTrials.gov/show/NCT00642564 Completed Johnson & Johnson Taiwan Ltd 2009-03-31
NCT00614549 Efficacy and Safety of Levetiracetam in Routine Clinical Practice in Czech and Slovak Republics, Hungary, and Romania. https://ClinicalTrials.gov/show/NCT00614549 Completed UCB Pharma 2009-06-30
NCT00612235 Premenstrual Dysphoric Disorder and Antiepileptic Drugs https://ClinicalTrials.gov/show/NCT00612235 Completed Beth Israel Deaconess Medical Center 2010-06-30
NCT00600717 Clinical Applications of High-Frequency Oscillations https://ClinicalTrials.gov/show/NCT00600717 Enrolling by invitation Children’s Hospital Medical Center, Cincinnati 2020-07-01
NCT00587951 The Influence of SISCOM on Intracranial Electrode Implantation in Epilepsy Surgical Candidates https://ClinicalTrials.gov/show/NCT00587951 Completed Mayo Clinic 2007-02-28
NCT00552045 Epilepsy Phenome/Genome Project https://ClinicalTrials.gov/show/NCT00552045 Completed University of California, San Francisco 2013-12-31
NCT00550940 Emotion/Behavior Problems, Neuropsychological Functioning, and Parental Adjustment in Children With Epilepsy https://ClinicalTrials.gov/show/NCT00550940 Completed National Taiwan University Hospital NA
NCT00522522 Naturalistic Study to Evaluate the Utilization of Care Services Associated to the Diagnostic Process of Any Kind of Epilepsy https://ClinicalTrials.gov/show/NCT00522522 Completed UCB Pharma 2008-07-31
NCT00497835 Study of Algorithm for Epilepsy Alert Device https://ClinicalTrials.gov/show/NCT00497835 Completed Biolert 2010-10-31
NCT00460070 Study of Hormonal Sideeffects in Patients Taking Levetiracetam, Carbamazepine or Lamotrigine for Epilepsy https://ClinicalTrials.gov/show/NCT00460070 Completed Rikshospitalet University Hospital NA
NCT00394927 Adverse Event Scale in Patients With Epilepsy (aEscape) - A European Survey for Physicians With Epilepsy Patients https://ClinicalTrials.gov/show/NCT00394927 Completed UCB Pharma 2007-08-31
NCT00393666 Why Are Patients With Absence Seizures Absent? A Brain Imaging Study https://ClinicalTrials.gov/show/NCT00393666 Completed Yale University 2015-09-30
NCT00365482 Bipolar Disorder in Epilepsy https://ClinicalTrials.gov/show/NCT00365482 Completed Northwell Health 2011-12-31
NCT00356018 Compliance With Once-Daily Divalproex Extended-Release Tablets (Depakote-ER) Versus Multiple-Daily Dose Valproic Acid Capsules (Depakene) in Epilepsy: https://ClinicalTrials.gov/show/NCT00356018 Completed Orlando Health, Inc. NA
NCT00353886 Study of Antiepileptic Drug Effects on Child Development https://ClinicalTrials.gov/show/NCT00353886 Completed Augusta University NA
NCT00345475 UCB Antiepileptic Drugs (AED) Pregnancy Registry (Formerly the Keppra® Pregnancy Registry) https://ClinicalTrials.gov/show/NCT00345475 Completed UCB Pharma 2016-05-31
NCT00344877 Electrical Brain Stimulation to Reduce Epileptic Seizures https://ClinicalTrials.gov/show/NCT00344877 Completed National Institutes of Health Clinical Center (CC) NA
NCT00319605 Cross Sectional Study to Evaluate the Acceptability of Oral Solution of Levetiracetam https://ClinicalTrials.gov/show/NCT00319605 Completed UCB Pharma 2006-07-31
NCT00302991 Quality of Life and Adverse Effects in Epilepsy Patients (EPIKA) https://ClinicalTrials.gov/show/NCT00302991 Completed UCB Pharma 2007-10-31
NCT00299793 Observational Study of Lamotrigine https://ClinicalTrials.gov/show/NCT00299793 Completed Northwell Health NA
NCT00298818 Open Label Study of Zonisamide in the Treatment of Epilepsy in Patients With Mental Retardation https://ClinicalTrials.gov/show/NCT00298818 Completed Northwell Health 2005-12-31
NCT00297349 A Study of the Safety of Topiramate Given in Combination With Other Medications in Adults and Children With Seizures https://ClinicalTrials.gov/show/NCT00297349 Completed Janssen Cilag Pharmaceutica S.A.C.I., Greece NA
NCT00297323 An Observational Study of the Safety of Topiramate in Adults and Children With Epilepsy https://ClinicalTrials.gov/show/NCT00297323 Completed Janssen Cilag Pharmaceutica S.A.C.I., Greece NA
NCT00296413 A Study to Look at Antiepileptic Drug Levels While on Lamictal or Depakote With or Without an Oral Contraceptive https://ClinicalTrials.gov/show/NCT00296413 Completed Beth Israel Deaconess Medical Center 2009-02-28
NCT00277368 A Study of the Prevalence of Headache in Epileptic Patients https://ClinicalTrials.gov/show/NCT00277368 Completed Janssen Korea, Ltd., Korea NA
NCT00264680 Spanish Validation Of Quality of Life Questionnaire (QOLIE-10) For Epilepsy https://ClinicalTrials.gov/show/NCT00264680 Completed GlaxoSmithKline 2006-03-01
NCT00242905 Functional Magnetic Resonance Imaging (fMRI) Study of Memory in Children https://ClinicalTrials.gov/show/NCT00242905 Completed Assistance Publique - Hôpitaux de Paris 2009-02-28
NCT00204815 Bone Mineral Density in Pediatric Epilepsy https://ClinicalTrials.gov/show/NCT00204815 Completed University of Wisconsin, Madison NA
NCT00204360 Pediatric Epilepsy Database https://ClinicalTrials.gov/show/NCT00204360 Completed University of Alabama at Birmingham NA
NCT00203333 Cardiac Rhythm Abnormalities in Patients With Refractory Epilepsy at High Risk for Sudden Death https://ClinicalTrials.gov/show/NCT00203333 Completed Thomas Jefferson University 2007-06-30
NCT00195052 Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients https://ClinicalTrials.gov/show/NCT00195052 Active, not recruiting Weill Medical College of Cornell University 2020-12-31
NCT00179426 Effect of Antiseizure Medication on Hormone Levels and Sexual Function in Men With Epilepsy https://ClinicalTrials.gov/show/NCT00179426 Completed Beth Israel Deaconess Medical Center NA
NCT00152659 Developing Criteria for Cortical Resections https://ClinicalTrials.gov/show/NCT00152659 Recruiting University of Chicago 2030-12-31
NCT00144001 Factors Associated With in Suboptimal Prescribing for Older Patients With Epilepsy https://ClinicalTrials.gov/show/NCT00144001 Completed VA Office of Research and Development 2004-09-30
NCT00085683 Herpes Virus-6 and Epilepsy https://ClinicalTrials.gov/show/NCT00085683 Completed National Institutes of Health Clinical Center (CC) NA
NCT00081432 Language and Emotional Function in Patients With Temporal Lobe Epilepsy https://ClinicalTrials.gov/show/NCT00081432 Completed National Institutes of Health Clinical Center (CC) NA
NCT00072813 MRI in Autosomal Dominant Partial Epilepsy With Auditory Features https://ClinicalTrials.gov/show/NCT00072813 Completed National Institutes of Health Clinical Center (CC) 2009-11-12
NCT00071370 Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagnostic EEG https://ClinicalTrials.gov/show/NCT00071370 Completed National Institutes of Health Clinical Center (CC) NA
NCT00071305 Non-Invasive Seizure Localization in Patients With Medically Refractory Localization Related Epilepsy: Synchronized MEG-EEG Recordings https://ClinicalTrials.gov/show/NCT00071305 Completed National Institutes of Health Clinical Center (CC) 2009-10-06
NCT00001672 Language Localization Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Patients With Epilepsy https://ClinicalTrials.gov/show/NCT00001672 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001489 Effect of Vigabatrin on Brain Blood Flow and Glucose Metabolism https://ClinicalTrials.gov/show/NCT00001489 Completed National Institutes of Health Clinical Center (CC) NA
NCT00044252 Role of Hormones in Susceptibility to Seizures in Women With Epilepsy https://ClinicalTrials.gov/show/NCT00044252 Completed National Institutes of Health Clinical Center (CC) NA
NCT00041951 Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study https://ClinicalTrials.gov/show/NCT00041951 Completed Icahn School of Medicine at Mount Sinai 2014-07-31
NCT00036595 Functional Coupling of Cortico-Cortical and Cortico-Muscular Connections During Motor Movements: An Electrocorticographic Study of Ipsilateral Motor Control https://ClinicalTrials.gov/show/NCT00036595 Completed National Institutes of Health Clinical Center (CC) NA
NCT00025714 Study of Specimens Obtained During Epilepsy Surgery https://ClinicalTrials.gov/show/NCT00025714 Completed National Institutes of Health Clinical Center (CC) NA
NCT00021866 Developmental Effects On Children Of Women Who Take Antiepileptic Drugs During Pregnancy https://ClinicalTrials.gov/show/NCT00021866 Completed Emory University 2010-08-31
NCT00771927 Post-Authorization Safety Study to Assess the Safety of Vimpat as add-on Therapy in Patients With Partial-onset Seizures https://ClinicalTrials.gov/show/NCT00771927 Completed UCB Pharma 2012-03-31
NCT00006059 Genetic Study of Familial Epilepsy https://ClinicalTrials.gov/show/NCT00006059 Completed National Center for Research Resources (NCRR) NA
NCT00001666 Transcranial Magnetic Stimulation for the Treatment of Poorly Controlled Partial Epilepsy https://ClinicalTrials.gov/show/NCT00001666 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001366 Mapping the Areas of the Brain Associated With Language in Children With Epilepsy https://ClinicalTrials.gov/show/NCT00001366 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001325 Metabolic Abnormalities in Children With Epilepsy https://ClinicalTrials.gov/show/NCT00001325 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001288 Brain Blood Flow Studies of Language and Memory https://ClinicalTrials.gov/show/NCT00001288 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001149 Monitoring Patients With Uncontrolled Epilepsy https://ClinicalTrials.gov/show/NCT00001149 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001932 Serotonin Receptors in Seizure Disorders https://ClinicalTrials.gov/show/NCT00001932 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02954107 Longitudinal Early Epilepsy Study https://ClinicalTrials.gov/show/NCT02954107 Recruiting Maastricht University Medical Center 2019-09-30
NCT02572297 National Network for the Study of Predictors and Prevention of Sudden Unexpected Death in Drug-resistant Partial Epilepsies https://ClinicalTrials.gov/show/NCT02572297 Completed Hospices Civils de Lyon 2015-02-28
NCT02329028 Feasibility of Mini-EEG in the Prehospital Setting https://ClinicalTrials.gov/show/NCT02329028 Completed Helsinki University Central Hospital 2016-09-30
NCT02126774 The Human Epilepsy Project https://ClinicalTrials.gov/show/NCT02126774 Active, not recruiting NYU Langone Health 2020-06-01
NCT01764516 Study on Serum Zinc and Selenium Levels in Epileptic Patients https://ClinicalTrials.gov/show/NCT01764516 Completed Arak University of Medical Sciences 2012-03-31
NCT04171934 Clinical Validation of a Video-based Epilepsy Examination Service https://ClinicalTrials.gov/show/NCT04171934 Active, not recruiting Tampere University 2019-12-31
NCT03814174 Comparison of Physical Fitness and Activities of the Children With Epilepsy and Their Healthy Peers https://ClinicalTrials.gov/show/NCT03814174 Completed Hacettepe University 2018-05-20
NCT03655366 Epidogs International Inventory of Seizure Alert Dogs https://ClinicalTrials.gov/show/NCT03655366 Completed University Hospital, Ghent 2018-07-01
NCT03531008 Human Epilepsy Project 2: Resistant Focal Seizures Study https://ClinicalTrials.gov/show/NCT03531008 Recruiting Epilepsy Foundation of America 2020-07-31
NCT03529045 Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. https://ClinicalTrials.gov/show/NCT03529045 Recruiting LivaNova 2026-12-31
NCT01793168 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford https://ClinicalTrials.gov/show/NCT01793168 Recruiting Sanford Health 2100-12-31